株式会社日本生物製剤Japan Bio Products Co., Ltd.

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TOP > Company Profile > SAFETY of JBP Placental Extract (Human)

Company Profile

SAFETY of JBP Placental Extract (Human)

Safety Criteria of JBP Placental Extract (Human)

  1. Donor Screening
  2. Acceptance Inspection Test
  3. Sterilization by 3 Different Methods
  4. Product Specification Test

Donor Screening

  1. Tested Negatives for all virus & bacteria tests including HBV, HCV, HIV, Treponema pallidum etc.
  2. Screening of Donor’s overseas staying experience
  3. Donor consent to use as a pharmaceutical ingredient

Acceptance Inspection Test

  1. Individual inspection by weight, color, smell, etc.
  2. NAT testing for HBV-DNA, HCV-RNA, HIV-1-RNA of all samples.
  3. Accepted

Sterilization by 3 Different Methods

  1. With organic solvent (acetone)
  2. With digestive enzyme + acid processing
  3. With 121℃ × 20 minutes autoclave (final sterilization)

Product Specification Test

Before approved for shipment, the product must show “negative” for:

  1. HBV
  2. HCV
  3. HIV
  4. HTLV
  5. Parvovirus-B19

Sterilizaion, combining several different mechanisms

Viral test at contracted obstetricians, re-tested at factory

Viral test of finished product